In my small corner of the world the biggest upcoming change is going to be the widespread use of Linux, Tablets, and RISC based processors. Of course the old advances are still there (no mechanical parts, 100% DC, etc.) and are going to be very important to the transition. More affordable computers with a new input and command system.
All of the Zen alliance websites will need to be updated for ease of use. I had a chance to test some of the Android tablets out over the Winter and immediately noticed some problems with how we compact information on websites. Simple spacing will be used to get past this problem so that even the worst quality tablets can get a top quality experience on these websites. Good thing CSS3 got here in time with the border-radius function.